3 Things To Know About Teplizumab, the New Diabetes Drug > News > Yale Medicine

3 Things To Know About Teplizumab, the New Diabetes Drug > News > Yale Medicine

“Diabetes is a disease that is with you literally every minute of the day. You don’t sleep, exercise, or eat without thinking about your metabolic control,” says Dr. Herold. “People with diabetes will tell you that any time without the disease is a gift, particularly for young children and their parents. Some ask, ‘If you’re still going to get diabetes, what’s the big deal?’ But when you’re an eight-year-old child, if the time at which you need to take insulin, follow a prescribed diet, and monitor your blood sugar is delayed for two more years, that’s huge.” 

In childhood, those extra years matter—a high-schooler, for instance, may be better equipped to handle the burden of a chronic disease than a middle-schooler. The delay also reduces the amount of exposure over time a patient has to the high blood sugars that cause a wide range of health complications. And as therapies for diabetes continue to evolve, there will likely be more improved and convenient options for patients.

What’s more, for half of patients, Dr. Herold says, their delays will be much longer than that. For instance, one high school student in this trial was diabetes-free for 11 years after treatment with teplizumab.

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